Posts made in ottobre, 2012

Resveratrol food supplements are actually reliable?

Posted by on ott 23, 2012 in News

Resveratrol food supplements are actually reliable?

According to our philosophy, laboratory data available for pure phytochemicals should translate into evidences from commercially available products. With this aim we have screened 14 commercial brands of resveratrol food supplements in order to verify their trans-resveratrol content at time of sale and to determine if their health-promoting properties are related to manufacturing quality. Results show that pharmaceutical-grade production should not be taken for granted by regulators and consumers, whose critical appraisal to these products must be fostered and suggest that an erratic...

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Human data: sylimarin absorbtion and metabolism

Posted by on ott 18, 2012 in News

Human data: sylimarin absorbtion and metabolism

Within the field of Human Nutrition, LS9 has a specific dedication to polyphenolic bioavailability. In our latest publication, we evaluated  the  absorption  and  metabolism  of  milk  thistle  flavonolignans  silychristin,  silydianin,  silybin  and  isosilybin  isomers  (all  together  known  as  silymarin)  in  humans. Milk  thistle  flavonolignans  are  extensively  modified  after  ingestion  and  recovered  in  urine as  sulpho-  and  glucuronyl-conjugates,  indicating  a  strong  affinity  for  hepatic  phase  II  enzymes.  All  future...

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A new method for the determination of pentacyclic triterpenic acids in botanicals

Posted by on ott 18, 2012 in News

A new method for the determination of pentacyclic triterpenic acids in botanicals

The occurrence of triterpene pentacyclic acids in plants is extensive, but little is known about their availability in commercial extracts. Thus, we developed a simple GC–MS method for the simultaneous determination of betulinic, corosolic, maslinic, oleanolic and ursolic acids that was applied to 38 different commercial plant extracts sold as ingredients for dietary supplements. A suitable protocol was set up to perform routine control of a diverse array of samples with different botanical, chemical and physical characteristics. Remarkable quantities of corosolic acid were found in dried...

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LS9 on masked mycotoxins

Posted by on ott 18, 2012 in News

LS9 on masked mycotoxins

Plants can alter the chemical structure of mycotoxins as part of their defence against xenobiotics and can thus accumulate potential toxic substances called “masked mycotoxins”, whose impact on human and animal health is still not properly elucidated. At LS9 we have a specific expertise in different kinds of mycotoxins and recently we have contributed to a comprehensive review on such topic. The paper...

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A new method to detect saffron adulteration

Posted by on ott 17, 2012 in News

A new method to detect saffron adulteration

The Journal of Agricultural and Food Chemistry has recently published our new method for quality control in saffron trade. The method, based on molecular markers, can detect up to 1% of each of the most common adulterants of ground Crocus sativus (L.): Arnica montana L., Bixa orellana L., Calendula officinalis L., Carthamus tinctorius L., Crocus vernus L. (Hill), Curcuma longa L. and Hemerocallis sp. It allows the preemptive rejection of suspect samples also in dried and long-time stored saffron batches. The...

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LS9 on the main italian newspaper

Posted by on ott 17, 2012 in News

LS9 on the main italian newspaper

The main italian newspaper, Corriere della Sera, asked us an opinion regarding the purported health-benefits of resveratrol and...

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LS9 on Antioxidant & Redox Signaling

Posted by on ott 17, 2012 in News

LS9 on Antioxidant & Redox Signaling

We have published a new comprehensive review named Dietary (Poly)phenolics in Human Health: Structures, Bioavailability and Evidence of Protective Effects Against Chronic Diseases in Antioxidants & Redox Signaling Journal (IF = 8.45). With 75 pages, 14 tables, 50 figures and more than 500 bibliographic references this review covers (almost) every aspect regarding polyphenols and their interactions with the human body. Particular attention has been given to the actual bioavailability levels of polyphenols and their intestinal metabolites that can be obtained in the human body Thanks to the...

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